Can I just ask you just to describe the Ebola virus? BEATRICE HAHN: The African green monkeys, mandrills. Greg is one of the founders, and he and Jon gets talking. And so you took care of him 'til he died? JAD: And these are tree-dwelling little -- little guys? Even the Department of Military Sciences is stumbling in its response to the growing threat. JAD: But why then? It's gotten out of control. Ledger - it's already hit the fan. So suppose on one side of the cell, you've got the mangabey virus, and on the other side of the same cell you've got the spot-nosed guenon virus. And so the amount of changes that you see out there, the diversity, really, of the viruses in the AIDS population, well that becomes really good information. But then one day when he's crossing the street ... Three teenaged girls in their mother's car ... And they hit him and broke his leg in three places. All across the country artificial intelligence drive systems in cars, commuter. Had a fight? They happen at a predictable rate. One side is creating exotic transgenic monsters and genetically enhanced mercenary armies; the other is using 21st century technology to continue the Nazi Master Race program begun by Josef Mengele. Okay. To order from Mysterious Galaxy, go here. Maybe he had a bow and arrow, maybe he had a spear, and he kills a chimpanzee. Literally hundreds of different species they looked in. And again, by molecular work scientists have been able to determine that the chimp virus is actually ... Two different monkeys from two completely different species. The fate of the world hangs in the balance.... PUBLISHERS WEEKLY: "Plenty of man-to-zombie combat, a team traitor and a doomsday scenario add up to a fast and furious read. DAVID QUAMMEN: Fellow that I called the voyager. JON MOOALLEM: They made the whole thing up, and then they just went to go cast their protagonist. Is this a teeny, teeny, teeny one? JAD: And this is where for me at least, the story gets way bigger than I imagined. Perhaps the cut hunter gave the virus to a woman who then passed it on to a fisherman. I'm a professor of medicine and microbiology at the University of Pennsylvania. And each patient, each little circle was numbered. The toy plane is the exact replica of the one flown by the war hero. No one understood why he was traded. Maybe he had a bow and arrow, maybe he had a spear, and he kills a chimpanzee. There's no doubt. And then, you know, they kept track of her for a while. And that means that when Ebola gets into us, it has no great future. We'll be back in just a moment. That was actually both the beginning and also almost the end of Burke's career. I feel fine. SEAN: This was towards the end of Lynn and my visit to the island. You know, they're a high-flying team. These chimps were essentially penned in between these three rivers. You know, he has small hands, he likes to put them up against the big hands of the Five guys. ROBERT KRULWICH: So this is a story that begins when? A top-secret prototype stealth fighter is destroyed during a test flight. Everyone's favorite snarky, dangerous, idealistic, relentless covert operative is back, and this time he's brought friends. So what do you do in this situation? That's the big question for Ebola 2014. They hijack these enzymes to make copies of themselves. And then when I looked into it, I realized I didn't know the first thing about it. But I wanted to step in and say that in the middle of the show, we're gonna slip from looking back at a disease that started a way long time ago to examining a disease that, you know, as I speak, this is happening right now. And Ebola doesn't have the right grappling hooks to lay hold of cells in the respiratory tract and get in them and then come bursting out of them and be carried outward on your breath. All these cases. This time 151 people die, and then it just disappears. By then, it had spread from these small villages into larger cities in part David says, because well, previous outbreaks had been in very remote places, it now found itself in a more densely-populated area. SEAN: So George Soper's like, "I've got to find this woman." He was bedridden. And that seems to have been the place from which the disease went global. Why wouldn't this guy be patient seven million? Now we got to investigate that. There are essentially 12 major groups of the HIV virus. Patient Zero is an action horror film set against the outbreak of a deadly virus that threatens to wipe out the human race. Afros, huge smiles, and their hands are in the air right about to connect. And to make a long story short ... At a time when Gaëtan Dugas was still a virginal adolescent. On 28 April 2016, the film was delayed to 17 February 2017. the stakes increase as it becomes clear that the end-game of this campaign of terror is igniting the Yellowstone caldera, the super-volcano that could destroy America. Bingo here's a big pile of meat. The Sangha River, which is -- the Ngoko is a tributary of the Sangha. And in 1994, Burke is diagnosed with -- with HIV or AIDS. You know, our kids and our grandkids are gonna talk about this." JON MOOALLEM: Yeah, it makes people so happy. It's a -- it's a spaghetti-shaped virus. Nobody knows his name. She could have seen where she used to live. She must have thought ... DAVID ROSNER: What? Planes will fall, hospitals will go dark, no help will come. Joe Ledger and his team go on a wild hunt to stop the terrorists and uncover the global super-power secretly funding them. Former Army Ranger. Then the virus got into these poor neighborhoods like West Point, where people were living together in -- in crowded slum-like neighborhoods. JUDY LEVITT: And their daughter get sick. But if you keep reading it, and in fact, it's addressed to a lawyer, it's clear that she was fighting this. This time we've got a very different situation. Something crazy happens. JUDY LEVITT: Just completely vanishes. She felt perfectly healthy. That's another of the big questions. It's either gonna burn out and come to an end or we're gonna stop it. People certainly in central Africa have been eating monkeys for thousands of years. DAVID QUAMMEN: Eight of them came from monkeys, three of them came from chimps and one came from gorillas. This is a larger primate. JAD: And chimp zero eats that monkey and gets a spot-nosed guenon version of the AIDS virus, or the SIV virus inside it. Enemies old and new rise as America burns. So if you want a patient zero, really clear patient zero, it's some of these individuals that have been infected with these viruses. Steven Guyer and his colleagues published a paper in Science in early September which involved doing exactly that. Patient Zero. LUTHA BURKE DAVIS: He used to get heckled a lot, you know, from people in the bleachers and ... ROBERT: And even worse, according to a couple of different people his coach ... ROBERT: Would often introduce Glenn Burke this way. So there were rumors circulating, and the rumors reached the front office of the LA Dodgers. ROBERT: He's the guy they'd send out to all the press events. This is Kathy Gregory. That's our subject. Guerilla Games’ upscaled to a 5-floor office in Amsterdam in early 2019, with the new office location sitting on a whopping 7,300 square meters of space. Creepy because it was in such dissolution? [CLIP: And the only child of a family, a lovely daughter was dying of it.]. SEAN: Not yet. What movie can we make about the beginning of the AIDS epidemic? Maybe people are walking around for three or four weeks with an occasional vomiting episode, but they're not dying. It's bad because his first mission is to help stop a group of terrorists from releasing a dreadful bio-weapon that can turn ordinary people into zombies. She just vanishes? [laughs]. LUTHA BURKE DAVIS: You know, like meet the youngsters, or ... JON MOOALLEM: Here's the story about this picture. LUTHA BURKE DAVIS: He just genuinely loved people. We're the dead-end host of Ebola. National High-Five Day, which is a kind of a joke holiday that was invented by a group of high school friends, I think. Like a human being dropped off on Mars, maybe without a spacesuit. It's all in the details, all of the juice and problem. So the spillover is not a highly improbable event. This was towards the end of Lynn and my visit to the island. Wow, and did -- at the moment that Derek Smith did it did an asteroid fall on his head or something? I told him that he was getting other people sick with it. JAD: Starting us off today are our producers Lynn Levy and Sean Cole. Like, can we -- can we take a person who's got sick of Ebola in Sudan and compare it to a person who's sick of Ebola in the Congo, and compare that to a person who's sick of Ebola in Niger or in wherever. And so what it ends up spitting out is a hybrid. CARL ZIMMER: So in 1981, doctors for the first time described ... [NEWS CLIP: A mysterious newly-discovered disease ...], [NEWS CLIP: ... which affects mostly homosexual men.]. Bonus features include character profiles and a never-before-published glimpse behind the scenes of the Department of Military Sciences. They happen at a predictable rate. On one end, there are all of these medical, former medical buildings, including a giant hospital where they isolated tuberculosis patients. And she says the first person that she encountered was Typhoid Mary Mallon. I mean, even George Soper, the guy who hunted her down said it was contrary to the Constitution of the United States to hold her under the circumstance. Just like the peach juice. PATIENT ZERO UPDATED FINAL WEB TRANSCRIPT . I mean, some guy from outer space comes into your kitchen and says, "You're diseased and you're hurting people." Sees this woman, 5'6", blond hair, blue eyes. A lot of times he didn't sleep well at night, and we would sit up and talk. Eight of them came from monkeys, three of them came from chimps and one came from gorillas. It could function. Turns out Jon had already been poking around into this question of who invented the high-five, and he had stumbled on this photograph. And he says to fully understand this part of the patient -- or rather chimp zero narrative, you have to grasp how it is that chimps hunt. Our staff includes Ellen Horne, Soren Wheeler, Pat Walters, Tim Howard, Brenna Farrell, Lynn Levy and Sean Cole. My name is Jon Mooallem. For instance, it might mutate and adapt in such a way that it kills fewer people or kills them more slowly, and leaves people infectious for a longer period of time. This was like the most horrible seaside vacation. Related: TV Shows To Watch If You Like True Blood By the time The Passage season finale rolled around, Amy had been infected with the virus but was able to resist the more nefarious influences of the already-turned vampires including scientist-turned-patient-zero Dr. Tim Fanning (Jamie McShane) and murderess Shauna Babcock (Brianne Howey, The Exorcist). Former cop. The other guy in the picture is Dusty Baker. SEAN: Very nice. And their daughter get sick. Buy from your favorite Indie BooksellerBuy from Mysterious GalaxyBuy from AmazonBuy the iBook from iTunesBuy from Barnes & NobleBuy from PowellsBuy the Audio Book from Audible. Now, here's the problem. JAD: Glenn Burke was a center fielder for the LA Dodgers in the '70s. So -- so one thing that people started to do ... CARL ZIMMER: ... was to -- they went started going back and looking at people who had died. Real mad scientist stuff. Can we talk about them? DAVID QUAMMEN: And I imagined him sliding into Brazzaville around 1920. I'm living a moral life. And to think that it could all go back to this one guy just seemed unreal. These -- these enzymes, they're not necessarily that sticky. JAD: It's the ultimate patient zero story, really. He just took on this -- this aura as single-handedly causing an epidemic in the United States. Found zero traces of live Ebola virus. Dun dun dun dun! GREG HARRELL-EDGE: Absolutely. She felt perfectly healthy. SEAN: And the cook's name was Mary Mallon. Bye-bye. DAVID QUAMMEN: The Sangha River, which is -- the Ngoko is a tributary of the Sangha. In the Kibale National Forest in -- in southwestern Uganda. So by 1908, all the virus has to do is get from that tiny village where the cut hunter lived to one of the new cities. Designer bioweapons. But when he went around playing away games, other teams picked it up and it sort of spread out. Spillover's the term that scientists use to describe the moment when a virus in one species passes into another species. And to think that it could all go back to this one guy just seemed unreal. CARL ZIMMER: Well, there are a couple reasons we know it. Josephine Baker who sat on her in the ambulance before, she says that she goes and pays a visit and walks into the kitchen. You need some way of explaining how this disaster happened. DAVID QUAMMEN: Yeah, some people have been saying that it would be like mutations that allowed a giraffe to fly. A lot of people are gonna help us tell the story, but starting us off is science writer, Radiolab regular Carl Zimmer. Maberry's prose sears, his dialog cuts like a knife, and his characters crackle with life. There are rumors of alien-human hybrids living among us. JAD: Like we described before, you can measure the differences between the samples, calculate how long it would take for those samples to get that different. NATHAN WOLFE: Okay, boom!

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